The International Isotope Society UK Group 28th Annual Symposium is a one day event covering the synthesis and applications of isotopically labelled compounds to be held on Friday, 8th November 2019 at The Møller Centre in Cambridge, UK.

Highlights of the meeting will be a talks from Professor Adam Nelson (University of Leeds) on "How Best to explore chemical space for bioactive molecular discovery" and Professor Helen Hailes (University College London) on "Enzymatic approaches to natural and non-natural alkaloids."

Other topics will include organic synthesis with stable isotopes, isotopes of hydrogen, carbon and fluorine, the role of radiolabelled mass balance studies in small molecule development and selectivity challenges in catalysis. A detailed programme is in production and will be available in due course. A complete list of confirmed speakers and presentations follows:

Speakers & Talks

Professor Adam Nelson (University of Leeds, UK)
How best to explore chemical space for bioactive molecular discovery.

Professor Helen Hailes (University College London, UK)
Enzymatic approaches to natural and non-natural alkaloids.

Dr Stephen Madden (Charles River Laboratories, UK)
Do radiolabelled mass balance studies still have a role to play in the development of small molecule therapeutics?

Professor Bill Lockley (University of Surrey, UK)
Hydrogen isotope labelling via reductive dehalogenation: what can we do about chlorine?

Dr Matt Treadwell (Wales Research and Diagnostic PET Imaging Centre (PETIC), UK)
Fluorine promoted synthesis of 19/18F perfluorinated motifs.

Dr Robert Phipps (University of Cambridge, UK)
Harnessing non-covalent interactions to address selectivity challenges in catalysis.

Dr Daniela Roman (GlaxoSmithKline, UK)
Where did the labels go? Labelling of two Maturation Inhibitor assets.

Mr Nick Summerhill (Pharmaron, UK)
The synthesis of [11-14C]Doxycline.

Dr Niklaas Buurma (Cardiff University, UK)
Quantitative prediction of rate constants for aqueous racemization to avoid pointless stereoselective syntheses - can a physical organic chemist survive without deuterium?

Dr Rafael Torres Martin de Rosales (Kings College London, UK)
PET imaging of γδ T-cell immunotherapy and complementary nanomedicines.

Mr Ruediger Exner (University of Bath, UK)
Synthesis of simultaneously near-IR emitting and 89Zr-labelled multimodal imaging probes for prostate cancer.

Poster Session

There will also be an opportunity to present posters at the meeting and we will also be offering a prize for the best poster by a post-graduate — please contact if you would like to present a poster.


We are delighted to be returning to The Møller Centre again this year. The venue is approximately one mile from Junction 13 on the M11 motorway and a short taxi ride from Cambridge railway station with its frequent express services to Liverpool Street station and Stansted Airport. The meeting will be timed to allow most UK based people to travel to and from the symposium on the same day although accommodation is available at The Møller Centre for those travelling from afar.


The closing date for registration is Friday, 1st November 2019.

We hope you will be able to attend and help make this meeting of the IIS UK Group as successful as in previous years. A buffet lunch will be provided for all delegates.

Please register using the online registration form which also contains details on how to send your remittance and confirm your place.